Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases
- Creator: Iglesias, Adriana I. , Mishra, Aniket , Vitart, Veronique , Bykhovskaya, Yelena , Höhn, René , Springelkamp, Henriët , Cuellar-Partida, Gabriel , Gharahkhani, Puya , Bailey, Jessica N. Cooke , Willoughby, Colin E. , Li, Xiaohui , Yazar, Seyhan , Nag, Abhishek , Khawaja, Anthony P. , Polašek, Ozren , Siscovick, David , Mitchell, Paul , Tham, Yin Chung , Haines, Jonathan L. , Kearns, Lisa S. , Hayward, Caroline , Shi, Yuan , van Leeuwen, Elisabeth M. , Taylor, Kent D. , Wang, Jie Jin , Rochtchina, Elena , Attia, John , Scott, Rodney , Holliday, Elizabeth G. , Baird, Paul N. , Xie, Jing , Inouye, Michael , Viswanathan, Ananth , Sim, Xueling , Bonnemaijer, Pieter , Rotter, Jerome I. , Martin, Nicholas G. , Zeller, Tanja , Mills, Richard A. , Staffieri, Sandra E. , Jonas, Jost B. , Schmidtmann, Irene , Boutin, Thibaud , Kang, Jae H. , Lucas, Sionne E. M. , Wong, Tien Yin , Beutel, Manfred E. , Wilson, James F. , Allingham, R. Rand , Brilliant, Murray H. , Budenz, Donald L. , Christen, William G. , Fingert, John , Friedman, David S. , Gaasterland, Douglas , Gaasterland, Terry , Hauser, Michael A. , Kraft, Peter , Lee, Richard K. , Lichter, Paul R. , Liu, Yutao , Loomis, Stephanie J. , Moroi, Sayoko E. , Pericak-Vance, Margaret A. , Realini, Anthony , Richards, Julia E. , Schuman, Joel S. , Scott, William K. , Singh, Kuldev , Sit, Arthur J. , Vollrath, Douglas , Weinreb, Robert N. , Wollstein, Gadi , Zack, Donald J. , Zhang, Kang
- Resource Type: journal article
- Date: 2018
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function
- Creator: Pattaro, Cristian , Teumer, Alexander , Taliun, Daniel , Wallaschofski, Henri , Vöelzke, Henry , Brenner, Hermann , Kroemer, Heyo K. , Kramer, Holly , Lin, Honghuang , Leach, I. Mateo , Ford, Ian , Guessous, Idris , Rudan, Igor , Olden, Matthias , Prokopenko, Inga , Borecki, Ingrid , Heid, Iris M. , Kolcic, Ivana , Persico, Ivana , Jukema, J. Wouter , Wilson, James F. , Felix, Janine F. , Divers, Jasmin , Lambert, Jean-Charles , Foster, Meredith , Stafford, Jeanette M. , Gaspoz, Jean-Michel , Smith, Jennifer A. , Faul, Jessica D. , Wang, Jie Jin , Ding, Jingzhong , Hirschhorn, Joel N. , Attia, John , Whitfield, John B. , Chalmers, John , Yang, Qiong , Viikari, Jorma , Coresh, Josef , Denny, Joshua C. , Karjalainen, Juha , Fernandes, Jyotika K. , Endlich, Karlhans , Butterbach, Katja , Keene, Keith L. , Lohman, Kurt , Portas, Laura , Chen, Ming-Huei , Launer, Lenore J. , Lyytikäinen, Leo-Pekka , Yengo, Loic , Franke, Lude , Ferrucci, Luigi , Rose, Lynda M. , Kedenko, Lyudmyla , Rao, Madhumathi , Struchalin, Maksim , Kleber, Marcus E. , Pers, Tune H. , Cavalieri, Margherita , Haun, Margot , Cornelis, Marilyn C. , Ciullo, Marina , Pirastu, Mario , de Andrade, Mariza , McEvoy, Mark A. , Woodward, Mark , Adam, Martin , Cocca, Massimiliano , Johnson, Andrew D. , Nauck, Matthias , Imboden, Medea , Waldenberger, Melanie , Pruijm, Menno , Metzger, Marie , Stumvoll, Michael , Evans, Michele K. , Sale, Michele M. , Käehöenen, Mika , Boban, Mladen , Ko, Yi-An , Bochud, Murielle , Rheinberger, Myriam , Verweij, Niek , Bouatia-Naji, Nabila , Martin, Nicholas G. , Hastie, Nick , Probst-Hensch, Nicole , Soranzo, Nicole , Devuyst, Olivier , Raitakari, Olli , Fuchsberger, Christian , Gottesman, Omri , Franco, Oscar H. , Polasek, Ozren , Gasparini, Paolo , Munroe, Patricia B. , Ridker, Paul M. , Mitchell, Paul , Muntner, Paul , Meisinger, Christa , Smit, Johannes H. , Tayo, Bamidele , Kovacs, Peter , Wild, Philipp S. , Froguel, Philippe , Rettig, Rainer , Mäegi, Reedik , Biffar, Reiner , Schmidt, Reinhold , Middelberg, Rita P. S. , Carroll, Robert J. , Penninx, Brenda W. , Gorski, Mathias , Nalls, Michael , Scott, Rodney J. , Katz, Ronit , Sedaghat, Sanaz , Wild, Sarah H. , Kardia, Sharon L. R. , Ulivi, Sheila , Hwang, Shih-Jen , Enroth, Stefan , Kloiber, Stefan , Trompet, Stella , Feitosa, Mary F. , Stengel, Benedicte , Hancock, Stephen J. , Turner, Stephen T. , Rosas, Sylvia E. , Stracke, Sylvia , Harris, Tamara B. , Zeller, Tanja , Zemunik, Tatijana , Lehtimäki, Terho , Illig, Thomas , Isaacs, Aaron , Aspelund, Thor , Nikopensius, Tiit , Esko, Tonu , Tanaka, Toshiko , Gyllensten, Ulf , Völker, Uwe , Emilsson, Valur , Vitart, Veronique , Aalto, Ville , Gudnason, Vilmundur , Dehghan, Abbas , Chouraki, Vincent , Chen, Wei-Min , Igl, Wilmar , März, Winfried , Koenig, Wolfgang , Lieb, Wolfgang , Loos, Ruth J. F. , Liu, Yongmei , Snieder, Harold , Pramstaller, Peter P. , d'Adamo, Pio , Parsa, Afshin , O'Connell, Jeffrey R. , Susztak, Katalin , Hamet, Pavel , Tremblay, Johanne , de Boer, Ian H. , Böger, Carsten A. , Goessling, Wolfram , Chasman, Daniel I. , Köttgen, Anna , Adeyemo, Adebowale , Kao, W. H. Linda , Fox, Caroline S. , ICBP Consortium , AGEN Consortium , CARDIOGRAM , CHARGe-Heart Failure Group , ECHOGen Consortium , Dieffenbach, Aida Karina , Zonderman, Alan B. , Nolte, Ilja M. , van der Most, Peter J. , Chu, Audrey Y. , Wright, Alan F. , Shuldiner, Alan R. , Morrison, Alanna C. , Hofman, Albert , Smith, Albert V. , Dreisbach, Albert W. , Franke, Andre , Uitterlinden, Andre G. , Metspalu, Andres , Tonjes, Anke , Li, Man , Lupo, Antonio , Robino, Antonietta , Johansson, Åsa , Demirkan, Ayse , Kollerits, Barbara , Freedman, Barry I. , Ponte, Belen , Oostra, Ben A. , Paulweber, Bernhard , Kräemer, Bernhard K. , Mijatovic, Vladan , Mitchell, Braxton D. , Buckley, Brendan M. , Peralta, Carmen A. , Hayward, Caroline , Helmer, Catherine , Rotimi, Charles N. , Shaffer, Christian M. , Müeller, Christian , Sala, Cinzia , van Duijn, Cornelia M. , Garnaas, Maija , Saint-Pierre, Aude , Ackermann, Daniel , Shriner, Daniel , Ruggiero, Daniela , Toniolo, Daniela , Lu, Yingchang , Cusi, Daniele , Czamara, Darina , Ellinghaus, David , Siscovick, David S. , Tin, Adrienne , Ruderfer, Douglas , Gieger, Christian , Grallert, Harald , Rochtchina, Elena , Atkinson, Elizabeth J. , Holliday, Elizabeth G. , Boerwinkle, Eric , Salvi, Erika , Bottinger, Erwin P. , Murgia, Federico , Sorice, Rossella , Rivadeneira, Fernando , Ernst, Florian , Kronenberg, Florian , Hu, Frank B. , Navis, Gerjan J. , Curhan, Gary C. , Ehret, George B. , Homuth, Georg , Coassin, Stefan , Thun, Gian-Andri , Li, Yong , Pistis, Giorgio , Gambaro, Giovanni , Malerba, Giovanni , Montgomery, Grant W. , Eiriksdottir, Gudny , Jacobs, Gunnar , Li, Guo , Wichmann, H-Erich , Campbell, Harry , Schmidt, Helena
- Resource Type: journal article
- Date: 2016
Genome-wide association analysis identifies six new loci associated with forced vital capacity
- Creator: Loth, Daan W. , Artigas, María Soler , Lee, Mi Kyeong , Scott, Rodney J. , Karrasch, Stefan , Grallert, Harald , Gaddis, Nathan C. , Starr, John M. , Wijmenga, Cisca , Minster, Ryan L. , Lederer, David J. , Pekkanen, Juha , Gyllensten, Ulf , Strachan, David P. , Campbell, Harry , Morris, Andrew P. , Gläeser, Sven , Hammond, Christopher J. , Burkart, Kristin M. , Beilby, John , Kritchevsky, Stephen B. , Gucinason, Vilmundur , Hancock, Dana B. , Williams, O. Dale , James, Alan L. , Polasek, Ozren , Zemunik, Tatijana , Kolcic, Ivana , Petrini, Marcy F. , Wjst, Matthias , Kim, Woo Jin , Porteous, David J. , Scotland, Generation , Smith, Blair H. , Viljanen, Anne , Huffman, Jennifer E. , Heliovaara, Markku , Attia, John R. , Sayers, Ian , Hampel, Regina , Gieger, Christian , Deary, Ian J. , Boezen, H. Marike , Newman, Anne , Jarvelin, Marjo-Riitta , Wilson, James F. , Vitart, Veronique , Lind, Lars , Stricker, Bruno H. , Teumer, Alexander , Spector, Timothy D. , Melén, Erik , Peters, Marjolein J. , Lange, Leslie A. , Barr, R. Graham , Bracke, Ken R. , Verhamme, Fien M. , Ramasamy, Adaikalavan , Sung, Joohon , Hiemstra, Pieter S. , Cassano, Patricia A. , Sood, Akshay , Hayward, Caroline , Dupuis, Josée , Hall, Ian P. , Brusselle, Guy G. , Tobin, Martin D. , London, Stephanie J. , Wareham, Nicholas J. , Kaprio, Jaakko , Wang, Xin-Qun , Trochet, Holly , Gharib, Sina A. , Kähönen, Mika , Flexeder, Claudia , Albrecht, Eva , Lopez, Lorna M. , de Jong, Kim , Thyagarajan, Bharat , Alves, Alexessander Couto , Enroth, Stefan , Omenaas, Ernst , Joshi, Peter K. , Wain, Louise V. , Fall, Tove , Viñuela, Ana , Launer, Lenore J. , Loehr, Laura R. , Fornage, Myriam , Li, Guo , Wik, Jemma B. , Tang, Wenbo , Manichaikul, Ani , Lahousse, Lies , Franceschini, Nora , Harris, Tamara B. , North, Kari E. , Rudnicka, Alicja R. , Hui, Jennie , Gu, Xiangjun , Lumley, Thomas , Wright, Alan F. , Hastie, Nicholas D. , Campbell, Susan , Kumar, Rajesh , Koch, Beate , Pin, Isabelle , Scott, Robert A. , Pietilainen, Kirsi H. , Surakka, Ida , Liu, Yongmei , Holliday, Elizabeth G. , Schulz, Holger , Heinrich, Joachim , Davies, Gail , Vonk, Judith M. , Pottinger, Tess D. , Wojczynski, Mary , Pouta, Anneli , Johansson, Åsa , Wild, Sarah H. , Ingelsson, Erik , Rivadeneira, Fernando , Vöezke, Henry , Hysi, Pirro G. , Eiriksdottir, Gudny , Morrison, Alanna C. , Smith, Albert Vernon , Rotter, Jerome I. , Gao, Wei , Postma, Dirkje S. , White, Wendy B. , Rich, Stephen S. , Hofman, Albert , Aspelund, Thor , Couper, David , Smith, Lewis J. , Psaty, Bruce M. , Duan, Qing , Lohman, Kurt , Burchard, Esteban G. , Uitterlinden, André G. , Garcia, Melissa , Joubert, Bonnie R. , McArdle, Wendy L. , Musk, A. Bill , Hansel, Nadia , Heckbert, Susan R. , Zgaga, Lina , Oldmeadow, Chris , van Meurs, Joyce B. J. , Navarro, Pau , Rudan, Igor , Oh, Yeon-Mok , Redline, Susan , Jarvis, Deborah L. , Zhao, Jing Hua , Rantanen, Taina , O'Connor, George T. , Ripatti, Samuli
- Resource Type: journal article
- Date: 2014
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
- Creator: Köttgen, Anna , Albrecht, Eva , Yang, Qiong , Tanaka, Toshiko , Johnson, Andrew D. , Kutalik, Zoltán , Smith, Albert V. , Shi, Julia , Struchalin, Maksim , Middelberg, Rita P. S. , Brown, Morris J. , Gaffo, Angelo L. , Teumer, Alexander , Oldmeadow, Christopher , Scott, Rodney J. , Holliday, Elizabeth G. , Attia, John , Vitart, Veronique , Krumsiek, Jan , Hundertmark, Claudia , Pistis, Giorgio , Ruggiero, Daniela , O'Seaghdha, Conall M. , Haller, Toomas
- Resource Type: journal article
- Date: 2013
Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error
- Creator: Stambolian, Dwight , Wojciechowski, Robert , Wong, Tien Y. , Simpson, Claire L. , Klaver, Caroline C. W. , van Duijn, Cornelia M. , Verhoeven, Virginie J. M. , Baird, Paul N. , Vitart, Veronique , Paterson, Andrew D. , Mitchell, Paul , Saw, Seang Mei , Oexle, Konrad , Holliday, Elizabeth G. , Attia, John , Scott, Rodney J. , Pirastu, Mario , Li, Xiaohui , Raffel, Leslie J. , Cotch, Mary Frances , Chew, Emily Y. , Klein, Barbara , Klein, Ronald
- Resource Type: journal article
- Date: 2013
Genome-wide association and functional follow-up reveals new loci for kidney function
- Creator: Pattaro, Cristian , Kottgen, Anna , Li, Man , Uitterlinden, Andre G. , Rivadeneira, Fernando , Aulchenko, Yurii S. , Polasek, Ozren , Hastie, Nick , Vitart, Veronique , Helmer, Catherine , Wang, Jie Jin , Ruggiero, Daniela , Bergmann, Sven , Gao, Xiaoyi , Kahonen, Mika , Viikari, Jorma , Nikopensius, Tiit , Province, Michael , Ketkar, Shamika , Colhoun, Helen , Doney, Alex , Robino, Antonietta , Giulianini, Franco , Kramer, Bernhard K. , Gorski, Mathias , Portas, Laura , Ford, Ian , Buckley, Brendan M. , Adam, Martin , Thun, Gian-Andri , Paulweber, Bernhard , Haun, Margot , Sala, Cinzia , Metzger, Marie , Mitchell, Paul , Yang, Qiong , Ciullo, Marina , King, Stuart K. , Vollenweider, Peter , Raitakari, Olli , Metspalu, Andres , Palmer, Colin , Gasparini, Paolo , Pirastu, Mario , Jukema, J. Wouter , Probst-Hensch, Nicole M. , Hundertmark, Claudia , Kronenberg, Florian , Toniolo, Daniela , Gudnason, Vilmundur , Shuldiner, Alan R. , Coresh, Josef , Schmidt, Reinhold , Ferrucci, Luigi , Siscovick, David S. , van Duijn, Cornelia M. , Borecki, Ingrid , Foster, Meredith C. , Kardia, Sharon L. R. , Liu, Yongmei , Curhan, Gary C. , Rudan, Igor , Gyllensten, Ulf , Wilson, James F. , Franke, Andre , Pramstaller, Peter P. , Retting, Rainer , Prokopenko, Inga , O'Seaghdha, Conall M. , Witteman, Jacqueline C. M. , Hayward, Caroline , Ridker, Paul , Parsa, Afshin , Bochud, Murielle , Heid, Iris M. , Goessling, Wolfram , Chasman, Daniel I. , Kao, W. H. Linda , Fox, Caroline S. , Glazer, Nicole , Isaacs, Aaron , Liu, Ching-Ti , Teumer, Alexander , Smith, Albert V. , O'Connell, Jeffrey R. , Struchalin, Maksim , Tanaka, Toshiko , Li, Guo , Johnson, Andrew D. , Gierman, Hinco J. , Feitosa, Mary , Hwang, Shih-Jen , Atkinson, Elizabeth J. , Garnaas, Maija , Lohman, Kurt , Cornelis, Marilyn C. , Johansson, Asa , Tonjes, Anke , Dehghan, Abbas , Chouraki, Vincent , Holliday, Elizabeth G. , Sorice, Rossella , Kutalik, Zoltan , Lehtimaki, Terho , Boger, Carsten A. , Esko, Tonu , Deshmukh, Harshal , Ulivi, Sheila , Chu, Audrey Y. , Murgia, Federico , Trompet, Stella , Imboden, Medea , Kollerits, Barbara , Pistis, Giorgio , CARDIoGRAM Consortium , Fuchsberger, Christian , ICBP Consortium , CARe Consortium , Wellcome Trust Case Control Consortium 2 (WTCCC2) , Harris, Tamara B. , Launer, Lenore J. , Aspelund, Thor , Eiriksdottir, Gudny , Mitchell, Braxton D. , Boerwinkle, Eric , Schmidt, Helena , Olden, Matthias , Cavalieri, Margherita , Rao, Madhumathi , Hu, Frank B. , Demirkan, Ayse , Oostra, Ben A. , de Andrade, Mariza , Turner, Stephen T. , Ding, Jingzhong , Andrews, Jeanette S. , Freedma, Barry I. , Chen, Ming-Huei , Koenig, Wolfgang , Illig, Thomas , Doring, Angela , Wichmann, H.-Erich , Kolcic, Ivana , Zemunik, Tatijana , Boban, Mladen , Minelli, Cosetta , Wheeler, Heather E. , Igl, Wilmar , Tin, Adrienne , Zaboli, Ghazal , Wild, Sarah H. , Wright, Alan F. , Campbell, Harry , Ellinghaus, David , Nothlings, Ute , Jacobs, Gunnar , Biffar, Reiner , Endlich, Karlhans , Ernst, Florian , Taliun, Daniel , Homuth, Georg , Kroemer, Heyo K. , Nauck, Matthias , Stracke, Sylvia , Volker, Uwe , Volzke, Henry , Kovacs, Peter , Stumvoll, Michael , Magi, Reedik , Hofman, Albert
- Resource Type: journal article
- Date: 2012